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Neuroblastoma PDCLs OPEN

Cell lines ending in “h” are established and grown in 5% O2. Cells ending in “h2” are established and grown in 2% O2.
Cells established and grown in serum-free neurobasal media will end with “nb”.

The definitions for the abbreviations are given below the table. Please scroll all the way down.

Please click at the top logo to return to home page.

How to Request a Cell Line:

Before you begin, please open the shipping cart in a browser tab and leave that tab open until you are ready to submit your request.

Open the cell line table list pages in a second tab and make all your selections in the second tab while leaving the cart open in the first tab.

You can check your selections and make deletions from the cart in the first tab at any time.

Just click on reload or refresh in the first tab to see any changes to the cart.

When you are ready, enter your shipping information on the cart page in the first tab and submit your completed request.

(1) Select the cell line(s)/PDXs by clicking each check box next to the cell line name.
(2) Fill out the institutional or commercial/industry information at the bottom of the page.
(3) Attach a fully signed MTA (including Attachment A)
(4) Attach any additional documents required for your request (i.e. a justification for any request over 10 cell lines total)
(5) Click Submit.

For all other questions regarding your request and/or MTA, please visit our FAQ page.

To view a complete cell line description (origin, growth conditions, pictures, etc.), click on the cell line name to open a pdf data sheet to view and/or download.


dbGaP info icon Childhood Cancer Data Initiative (CCDI): Pediatric In Vivo Testing Program - Neuroblastoma
dbGaP Study Accession: phs003163.v1.p1

dbGaP info icon Childhood Cancer Data Initiative (CCDI): CCDI Pediatric In Vivo Testing Program - Leukemia
dbGaP Study Accession: phs003164.v2.p1

PDXs in our Childhood Cancer Repository which can be found in the CCDI PIVOT data are marked with a dbGaP info icon dbGaP info icon in the table below.

 

The table below can be sorted by clicking on the column headers. You can sort multiple columns by holding down the Shift key while clicking on the column headers.

If you wish to reset it to the original sort order, just reload the page in your browser.

NeuroblastomaOxygen Condition
 2%5%20%5%
 Suffix
Request Cell Line Phase of Therapy Sample Type PDX MYCN ALK GD2 TH TMM p53 h2 h none hnb
 CHLA-100Dxtumor A       ✓ 
 CHLA-101Dxbone marrow A   TERT   ✓ 
 CHLA-105Dxbone marrow A       ✓ 
 CHLA-117BDxbone marrow         173 
 CHLA-122Dxbone marrow AWT++TERTF102 72 
 CHLA-123Dx blood A       ✓ 
 CHLA-126Dxbone marrow         116 
 CHLA-129Dxtumor         165 
 CHLA-137Dxtumor        98144 
 CHLA-138Dxbone marrow        107144 
 CHLA-139Dxbone marrow        7199 
 CHLA-14Dx  A  +TERT  117144 
 CHLA-142Dxbone marrow          ✓ 
 CHLA-143Dxbone marrow         ✓ 
 CHLA-144Dxbone marrow AWT+-TERT  60133 
 CHLA-15Dxtumor NR1275Q++TERTF50 21 
 CHLA-151Dxtumor A R1275Q +TMM-  124✓ 
 CHLA-152Dxtumor        107108 
 CHLA-153Dxbone marrow          ✓ 
 CHLA-16Dxpleural fluid NR1275Q +TERT  8089 
 CHLA-160Dxtumor A      9290 
 CHLA-27Dxbone marrow AF1174L      ✓ 
 CHLA-29Dxbone marrow AWT +TERT   ✓ 
 CHLA-30Dxtumor A  +TERT   ✓  
 CHLA-42Dxbone marrow NR1275Q +TERTF  ✓ 
 CHLA-43Dxbone marrow AWT      ✓ 
 CHLA-44Dxbone marrow N  +TERT   ✓ 
 CHLA-54Dx  A       ✓ 
 CHLA-78Dxbone marrow A     54 277 
 CHLA-83Dxbone marrow A     39 198 
 COG-N-261Dxtumor AWT +TERT   124 
 COG-N-263Dxtumor NWT +TERT   119 
 COG-N-265Dxtumor AWT +TERT   178 
 COG-N-276Dxbone marrow AWT +TERT   61 
 COG-N-278Dxtumor AWT +TERT   88 
 COG-N-293Dxtumor AWT +TERT   88 
 COG-N-294Dxtumor AR1275Q +TERTNF  350 
 COG-N-295Dxtumor NF1174L +TERT   58 
 COG-N-296Dxbone marrow A  +TMM-   347 
 COG-N-297Dxtumor AWT +TERT   28 
 COG-N-299Dxtumor AWT +TERT   347 
 COG-N-303Dxtumor AWT -TMM-   84 
 COG-N-305Dxtumor AWT +TERT   187 
 COG-N-311Dxbone marrow         ✓ 
 COG-N-312Dxbone marrow A  +TERT   35 
 COG-N-316Dxbone marrow A  +TERT   94 
 COG-N-320Dx tumor     TMM-   89 
 COG-N-322Dx tumor AWT +TERT   106 
 COG-N-323Dxtumor NWT      25 
 COG-N-324Dxbone marrow AWT +TERT   257 
 COG-N-328hDxtumor AWT +TERT  116  
 COG-N-331Dxbone marrow AWT +TERT   55 
 COG-N-333Dxbone marrow AF1174L +TERT   73 
 COG-N-347Dxbone marrow AWT +TERT  ✓126 
 COG-N-349Dxbone marrow AWT +TERT  ✓192 
 COG-N-353Dxbone marrow AWT +TERT  ✓144 
 COG-N-354Dxbone marrow A  +TERT  112  
 COG-N-367Dxbone marrow AR1275Q +TERT  ✓49✓
 COG-N-373Dxbone marrow AWT +TERT 182 126 
 COG-N-386hDxbone marrow     TERT  ✓  
 COG-N-442hDxbone marrow NWT +Unknown 57 98 
 COG-N-445Dxbone marrow AWT +TERT ✓90217✓
 COG-N-462hDxbone marrow AWT +TERT 120144  
 COG-N-474Dxbone marrow AF1174L +TERT ✓✓187 
 COG-N-480h2Dxbone marrow✓AWT +EST 277  158
 COG-N-490hDxbone marrow AWT +TERT  61  
 COG-N-491hDxblood AWT +TERT ✓198 ✓
 COG-N-496Dxbone marrow✓AWT++TERT 16513985✓
 COG-N-497Dxbone marrow A  +TERT ✓76✓✓
 COG-N-500Dxbone marrow N  +TERT   112✓
 COG-N-504Dxbone marrow N       315✓
 COG-N-509hnbDxbone marrow N  +EST    350
 COG-N-518hDxbone marrow✓N  +ESTN 267  
 COG-N-531hDxbone marrow A      ✓ ✓
 COG-N-532Dxbone marrow N   Unknown 55239✓✓
 COG-N-539Dxtumor A      ✓✓✓
 COG-N-540Dxbone marrow N   TERT ✓144267 
 COG-N-542hDxbone marrow A      ✓  
 COG-N-544Dxbone marrow N   Unknown ✓102✓✓
 COG-N-546hDxbone marrow✓A     161165 ✓
 COG-N-548Dxbone marrow N     161✓✓ 
 COG-N-554Dxbone marrow A     ✓✓✓ 
 COG-N-556Dxbone marrow A     ✓✓ ✓
 COG-N-557Dxbone marrow✓AF1245L+ TERT 124136114✓
 COG-N-562 Dxtumor N  +EST ✓✓✓ 
 COG-N-563Dxbone marrow A     ✓✓✓✓
 COG-N-571Dxbone marrow N      ✓✓ 
 COG-N-572hDxbone marrow N      ✓  
 COG-N-573Dxbone marrow✓AWT +TERT 25792239✓
 COG-N-574Dxbone marrow A     ✓✓✓✓
 COG-N-575Dxbone marrow A     ✓✓✓✓
 COG-N-581hDxbone marrow A     ✓✓  
 COG-N-582hDxbone marrow A     ✓✓  
 COG-N-585Dxbone marrow A     ✓✓✓✓
 COG-N-586Dxbone marrow A     ✓✓✓✓
 COG-N-590Dxtumor✓AWT++TERT  187277✓
 COG-N-600Dxbone marrow A     ✓✓✓✓
 COG-N-603Dxtumor✓AWT+ TERT 1175874✓
 COG-N-626hDxbone marrow       ✓✓ ✓
 COG-N-628Dxbone marrow✓AWT+   144103131 
 COG-N-636Dxtumor✓AWT+   12890154✓
 COG-N-651hDxbone marrow✓N   TERT 89315 ✓
 COG-N-675 Dxbone marrow N     98✓84158
 COG-N-682Dxbone marrow✓A   TERT 86596995
 COG-N-683Dxbone marrow✓A +   835377105
 COG-N-700Dxtumor✓N negTERT 161169144✓
 COG-N-708Dxtumor✓N +   N210257✓
 COG-N-709Dxtumor✓N     ✓114✓✓
 COG-N-732Dxtumor✓A   Unknown 17892169 
 COG-N-733Dxtumor A   Unknown ✓96117 
 COG-N-734Dxbone marrow A   TERT  9112484
 COG-N-740Dxtumor✓    Unknown ✓✓14773
 COG-N-742Dxtumor     Unknown  107 ✓
 COG-N-743hDxtumor✓    TERT 21777  
 COG-N-750Dxbone marrow   + ALT   120 
 COG-N-791Dxtumor✓    TERT  116✓ 
 COG-N-845Dxbone marrow✓    TERT ✓✓✓ 
 LA-N-2Dxtumor     TERT   ✓ 
 LA-N-5Dxbone marrow AR1275Q++TERT   100 
 NB-1643 dbGaP info iconDxtumor AR1275Q +TERT   ✓ 
 SK-N-BE(1)Dxbone marrow AWT +TERTF51 96 
 SMS-KANDxtumor AWT++TERTF62 95 
 SMS-KCNDxtumor AR1275Q++TERTF117 109 
 SMS-MSNDxbone marrow         ✓ 
 SMS-SANDxbone marrow AF1174L +TERTF  71 
 CHLA-102PDtumor A   ALT  7566 
 CHLA-103PDtumor A      112200+ 
 CHLA-108PDbone marrow A   Unknown 75 63 
 CHLA-109PDbone marrow     TERT   ✓ 
 CHLA-110PDbone marrow A      6053 
 CHLA-116PDbone marrow        92139 
 CHLA-118PDbone marrow         141 
 CHLA-119PDbone marrow AWT++TERTNF  88 
 CHLA-120PDtumor        200+  
 CHLA-125PDbone marrow A       ✓ 
 CHLA-127PDtumor         ✓ 
 CHLA-132PDbone marrow N  +TMM-   ✓ 
 CHLA-140PDbone marrow NWT +    ✓ 
 CHLA-145PDbone marrow AWT -TERT 60 128 
 CHLA-146PDbone marrow N       187 
 CHLA-150PDbone marrow NR1275Q     100112 
 CHLA-161PDbone marrow A       ✓ 
 CHLA-164PDbone marrow         ✓ 
 CHLA-183PDbone marrow N       36 
 CHLA-20PDtumor NR1275Q++TERTF45 28 
 CHLA-21PDbone marrow A       ✓ 
 CHLA-22PDbone marrow N       ✓ 
 CHLA-247PDbone marrow AWT +TERT   ✓ 
 CHLA-253PDtumor AWT  TERT   ✓ 
 CHLA-255PDtumor         ✓ 
 CHLA-28PDbone marrow AF1245C      ✓ 
 CHLA-34PDbone marrow N       ✓ 
 CHLA-41PDtumor AWT      ✓ 
 CHLA-46PDtumor AWT      ✓ 
 CHLA-58PDtumor         ✓ 
 CHLA-70PDbone marrow N + ALT   ✓ 
 CHLA-95PDtumor AR1275Q  TERT   248 
 COG-N-269PDtumor NWT -TERT   91 
 COG-N-289PDtumor A WT +TERT   38 
 COG-N-291PDbone marrow NWT +TMM-   224 
 COG-N-318PDtumor AWT +TERT   129 
 COG-N-321PDbone marrow A  +TERTNF65% 128 
 COG-N-325PDtumor AWT +    55 
 COG-N-327PDbone marrow AWT +TERT  ✓204 
 COG-N-334PDbone marrow AWT +TERT  ✓48 
 COG-N-346PDtumor NWT +TERT  ✓  
 COG-N-372hPDbone marrow NWT +TERT  ✓96 
 COG-N-381hPDfluid     TERT  36  
 COG-N-387hPDbone marrow AWT +  248267  
 COG-N-396hPDtumor     TERT  96  
 COG-N-443hPDbone marrow NF1245C +Unknown 10751✓ 
 COG-N-469hPDbone marrow NF1174L +TERT  70  
 COG-N-473hPDbone marrow AWT +TERT  100✓✓
 COG-N-475hPDtumor AR1275Q  TERT  96126 
 COG-N-478PDbone marrow NWT +TERT  ✓224✓
 COG-N-482hPDbone marrow A  +TERT  ✓  
 COG-N-507hPDbone marrow A   TERT  102  
 COG-N-508hPDbone marrow A   TERT  ✓  
 COG-N-511h2PDbone marrow N  +TERT ✓  ✓
 COG-N-512 PDbone marrow A     193 ✓ ✓
 COG-N-513PDbone marrow A     103✓✓✓
 COG-N-514PDbone marrow A      ✓✓✓
 COG-N-515PDbone marrow A +   ✓✓✓ 
 COG-N-549PDtumor✓NF1174L +  6067126✓
 COG-N-553PDbone marrow A + TERT 1207751✓
 COG-N-579hPDbone marrow✓N  +   120 ✓
 COG-N-618PDbone marrow✓NWT+   13157102 
 COG-N-619PDbone marrow✓NWT    819495 
 COG-N-623PDtumor✓AWT+   8388126✓
 COG-N-707PDbone marrow✓A +    7591 
 COG-N-711hPDblood N +    103  
 COG-N-731PDbone marrow✓A +    ✓ ✓ 
 COG-N-752PD bone marrow       350210165 
 COG-N-793hPDbone marrow   +    165  
 COG-N-818PDtumor✓    TERT ✓ ✓ 
 LA-N-1PDbone marrow AF1174L+ TERT   ✓ 
 LA-N-6PDbone marrow ND1091N +ESTF  150 
 NB-Ebc1 dbGaP info iconPDtumor NWT +    ✓ 
 SK-N-BE(2)PDbone marrow AWT++TERTNF37 27 
 SK-N-FIPDbone marrow NWT +ALT   ✓ 
 SMS-KANRPDbone marrow AWT +TERTF55 69 
 SMS-KCNRPDbone marrow AF1174L++TERTF45 72 
 SMS-LHNPDtumor N  +TERTF  216 
 CHLA-111bPD-BMTbone marrow         ✓ 
 CHLA-134PD-BMTbone marrow AWT + NF  ✓ 
 CHLA-136PD-BMTblood AWT++TERTF907844 
 CHLA-172PD-BMTbone marrow NWT + NF  110 
 CHLA-188LPD-BMTbone marrow AWT      ✓ 
 CHLA-188RPD-BMTbone marrow AWT      ✓ 
 CHLA-190PD-BMTtumor         ✓ 
 CHLA-51PD-BMTbone marrow NWT + F  ✓ 
 CHLA-79 dbGaP info iconPD-BMTtumor NWT +TERTF  ✓ 
 CHLA-8PD-BMTtumor AWT + F  ✓ 
 CHLA-90PD-BMTbone marrow NF1245Vneg-ALTNF  59 
 COG-N-476PD-BMTtumor AWT +TERT  ✓50✓
 CHLA-11PD-BMT, PMblood AWT++TERTN 7453 
 CHLA-12PD-BMT, PMbone marrow AWT +TERTN 5065 
 CHLA-171PD-PMperipheral blood NWT++TERTNF  89 
 CHLA-225PD-PMfluid AWT +TERTN  62 
 CHLA-52PD-PMbone marrow AF1174L +TERTN  86 
 CHLA-53PD-PMblood AF1174L +TERTN  92 
 CHLA-60PD-PMbone marrow NWT +TERTF  96 
 CHLA-61PD-PMblood NR1275Q +TERTF  102 
 COG-N-399PD-PMblood AWT +TERTF ✓40✓
 COG-N-415PD-PMblood✓A F1174L +TERT  6450✓
 COG-N-421PD-PMblood✓AWT++TERTN 6565 
 COG-N-440PD-PMblood✓AWT++TERTF14713665✓
 COG-N-452PD-PMblood✓AF1174L +TERTF20412274✓
 COG-N-453PD-PMtumor✓AWT +TERTF21012071✓
 COG-N-470PD-PMblood✓NF1174L +TERTF13910382 
 COG-N-471PD-PMblood✓AWT +TERTN   128
 COG-N-505PD-PMblood AWT++TERTF✓✓79 
 COG-N-519PD-PMblood✓AWTneg+TERTN635538✓
 COG-N-529PD-PMblood NWT +TERTF986981✓
 COG-N-534PD-PMblood NF1245C++TERTN ✓144 
 COG-N-536hPD-PMblood AR1275Q +TERTN✓128  
 COG-N-561PD-PMblood✓AF1245I +TERTF99124103✓
 COG-N-564hPD-PMblood✓A ++TERT 11698  
 COG-N-577PD-PMblood N  +TERT ✓✓✓✓
 COG-N-615PD-PMblood✓N  +TERT ✓117  
 COG-N-645PD-PMblood A   TERT ✓✓✓✓
 COG-N-660hnbPD-PMblood✓N   TERT  158 ✓
 COG-N-672PD-PMblood✓A + TERT  ✓80 
 COG-N-685PD-PMblood✓A   Unknown 126165 124
 COG-N-748PD-PMblood✓A   TERT  ✓139✓
 COG-N-813PD-PMblood✓N     ✓ ✓ 
 COG-N-815PD-PMblood✓A   TERT ✓✓✓✓
 COG-N-853PD-PMpost mortem blood✓    TERT ✓ ✓ 
 COG-N-863hPD-PMblood✓    TERT     
 Felix dbGaP info iconPD-PMblood✓NF1245V +TERTF 62277 
 FU-NB-2006PD-PMblood NWT +TERT  7248 
 CB-JHAN           ✓ 
 CB-JMN           ✓ 
 CHLA-104 bone marrow        161161 
 CHLA-106 bone marrow     TERT   ✓ 
 CHLA-124 tumor        124200 
 CHLA-13   N  +TERT  12296 
 CHLA-157 bone marrow     TERT   ✓ 
 CHLA-158 bone marrow     Unknown   ✓ 
 CHLA-159 tumor     Unknown   ✓ 
 CHLA-162 tumor        116✓ 
 CHLA-163 tumor        165231 
 CHLA-165 tumor        99136 
 CHLA-168 bone marrow        126100 
 CHLA-169 tumor        277✓ 
 CHLA-17   AWT      ✓ 
 CHLA-174 tumor N       ✓ 
 CHLA-175 tumor N       ✓ 
 CHLA-179 bone marrow A       ✓ 
 CHLA-18 bone marrow NWT +TERT  13399 
 CHLA-182 bone marrow     TERT   ✓ 
 CHLA-185 tumor     Unknown   ✓ 
 CHLA-19 bone marrow NWT     200+200+ 
 CHLA-234 tumor NWT      ✓ 
 CHLA-248 tumor         ✓ 
 LA-N-7       TERT   ✓ 

1 - Phase of therapy for the patient at the time the specimen used to derive the cell line was obtained
Dx (Diagnosis): cell lines derived from samples of patients prior to treatment
PD (Progressive Disease): cell lines derived from samples of patients who relapsed after chemotherapy
PD-BMT: cell lines derived from samples of patients who relapsed after chemotherapy and bone marrow transplantation
PD-PM: cell lines derived from samples of post-mortem patients who relapsed after chemotherapy

2 -MYCN oncogene amplification
N: MYCN Non-Amplified
A: MYCN Amplified

3 - TP53 gene function
F: Functional
N: Non-Functional

4 - EWS/FLI1 Status
FLI1: friend leukemia insertion - chromosome 11, t(11;22)
ERG: ets-related gene - chromosome 21, t(21;22)

ALK mutation

WT: Wild Type

TMM:Telomere Maintenance mechanism

✓ = Available/available upon request

SQ- subcutaneous injection

TV- intravenous (tail vein)

EST- ever shorter telomeres, i.e. telomerase and ALT negative

TERT+- telomerase positive

ALT - alternate lengthening of telomeres, C-circle positive