CHILDHOOD CANCER REPOSITORY

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Alex's Lemonade Stand Foundation

Pediatric Sarcomas

RequestCell LinePDXPhase of TherapyDiagnosisSample TypeAvailable Oxygen Conditions
      2% O25% O220% O2
COG-OS-551h--Osteosarcomapleural fluid--
Rh18-DxRhabdomyosarcomaperineum--
Rh30-DxRhabdomyosarcomabone marrow--
Rh41-PDRhabdomyosarcomalung tumor--
CB-NJR--Rhabdomyosarcomaunknown--
CHLA-33--Rhabdomyosarcomatumor--
CHLA-37-DxRhabdomyosarcomatumor--
COG-R-262-PD-BMTRhabdomyosarcomapericardial fluid--
 COG-R-438xPDRhabdomyosarcomatumor---
 COG-R-668xDxRhabdomyosarcomatumor---
SMS-CTR--Rhabdomyosarcoma, embryonal--

1 - Phase of therapy for the patient at the time the specimen used to derive the cell line was obtained
Dx (Diagnosis): cell lines derived from samples of patients prior to treatment
PD (Progressive Disease): cell lines derived from samples of patients who relapsed after chemotherapy
PD-BMT: cell lines derived from samples of patients who relapsed after chemotherapy and bone marrow transplantation
PD-PM: cell lines derived from samples of post-mortem patients who relapsed after chemotherapy

3 - TP53 gene function
F: Functional
N: Non-Functional

✓ = Available/available upon request

SQ- subcutaneous injection

TV- intravenous (tail vein)

EST- ever shorter telomeres, i.e. telomerase and ALT negative

TERT+- telomerase positive

ALT - alternate lengthening of telomeres, C-circle positive