CHILDHOOD CANCER REPOSITORY

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Alex's Lemonade Stand Foundation

Lymphoid Malignancies & Leukemia

RequestCell Line NamePDXPhase of DiseaseAge (years)Sample Type ReceivedDiagnosisAvailable Oxygen ConditionsGermline
       2% O25% O220% O2 
-COG-LL-330x  bone marrowAcute Lymphoblastic Leukemia (ALL)---Yes
-COG-LL-351x  bone marrowAcute Lymphoblastic Leukemia (ALL)---Yes
-COG-LL-377x  bone marrowAcute Lymphoblastic Leukemia (ALL)---No
-COG-LL-380x   Acute Lymphoblastic Leukemia (ALL)---No
-COG-LL-436xDx bone marrowAcute Lymphoblastic Leukemia (ALL)---Yes
CHLA-221    Acute Nonlymphocytic Leukemia (ANLL)-- 
COG-LL-319COG-LL-319xDx peripheral bloodPre-B Acute Lymphoblastic Leukemia (ALL)-No
 COG-LL-343x 16 Pre-B Acute Lymphoblastic Leukemia (ALL)---No
 COG-LL-350xDx4peripheral bloodPre-B Acute Lymphoblastic Leukemia (ALL)---No
COG-LL-355Dx7bone marrowPre-B Acute Lymphoblastic Leukemia (ALL)-No
COG-LL-402hCOG-LL-402xDx9bone marrowPre-B Acute Lymphoblastic Leukemia (ALL)---Yes
COG-LL-403hDx9peripheral bloodPre-B Acute Lymphoblastic Leukemia (ALL)-Yes
SMS-SB   tumorPre-B Acute Lymphoblastic Leukemia (ALL)-- 
COG-LL-317COG-LL-317xPD bone marrowT-cell Acute Lymphoblastic Leukemia (ALL)-No
COG-LL-329COG-LL-329xDx bone marrowT-cell Acute Lymphoblastic Leukemia (ALL)-No
COG-LL-332COG-LL-332xPD bone marrowT-cell Acute Lymphoblastic Leukemia (ALL)-No
COG-LL-384h PD  T-cell Acute Lymphoblastic Leukemia (ALL)--No
 COG-LL-489xDx peripheral blood (1st draw)T-cell Leukemia---Yes
 COG-LL-492xDx bone marrowT-cell Leukemia---Yes
 COG-LL-494xDx peripheral blood (2nd draw)T-cell Leukemia---Yes
 COG-LL-456xDx bone marrowLeukemia---Yes
COG-LL-528hCOG-LL-528xDx bone marrow (right draw)Leukemia-Yes
COG-LY-457COG-LY-457xPD-PM10bone marrow (autopsy)Burkitt's LymphomaYes
COG-LY-458PD-PM10blood (central vein) (autopsy)Burkitt's LymphomaYes
COG-LY-459 PD-PM10blood (left subclavian) (autopsy)Burkitt's LymphomaYes
COG-LY-460COG-LY-465xPD-PM10tumor/tumorBurkitt's Lymphoma-Yes
COG-LY-357-Dx bone marrowPre-T Lymphoblastic Lymphoma (LBL)-Yes

1 - Phase of therapy for the patient at the time the specimen used to derive the cell line was obtained
Dx (Diagnosis): cell lines derived from samples of patients prior to treatment
PD (Progressive Disease): cell lines derived from samples of patients who relapsed after chemotherapy
PD-BMT: cell lines derived from samples of patients who relapsed after chemotherapy and bone marrow transplantation
PD-PM: cell lines derived from samples of post-mortem patients who relapsed after chemotherapy

✓ = Available/available upon request

SQ- subcutaneous injection

TV- intravenous (tail vein)

EST- ever shorter telomeres, i.e. telomerase and ALT negative

TERT+- telomerase positive

ALT - alternate lengthening of telomeres, C-circle positive