CHILDHOOD CANCER REPOSITORY

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Wilm's

Cell lines ending in “h” are established and grown in 5% O2. Cells ending in “h2” are established and grown in 2% O2. Cells established and grown in serum-free neurobasal media will end with “nb”.

The defination for the abbreviation are given below the table. Please scroll all the way down.

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RequestCell LinePDXPhase of DiseaseSample Type ReceivedDiagnosispO2  
      2% O25% O220%O2
CHLA-64-Dx Wilms' Tumor--✓
COG-W-408-PDtumor, (relapse)Wilms' Tumor-✓✓
-COG-N-410x tumorWilms' Tumor---
-COG-W-477xPD-PMtumor (autopsy)Wilms' tumor---
-COG-W-661xDxtumorWilms' Tumor---

1 - Phase of therapy for the patient at the time the specimen used to derive the cell line was obtained
Dx (Diagnosis): cell lines derived from samples of patients prior to treatment
PD (Progressive Disease): cell lines derived from samples of patients who relapsed after chemotherapy
PD-BMT: cell lines derived from samples of patients who relapsed after chemotherapy and bone marrow transplantation
PD-PM: cell lines derived from samples of post-mortem patients who relapsed after chemotherapy

✓ = Available/available upon request